Glutathione (GSH) is a naturally occurring tripeptide composed of glutamic acid, cysteine, and glycine, linked through a unique gamma-glutamyl bond. It is classified as the principal intracellular non-protein thiol and functions as a central regulator of cellular redox balance, detoxification chemistry, and thiol-dependent enzymatic activity.
Through its free cysteine sulfhydryl group, glutathione participates in reversible oxidation and reduction cycles that neutralize reactive oxygen species, regenerate other antioxidants, and modulate redox-sensitive signaling pathways. Glutathione also serves as a substrate for glutathione S-transferases in xenobiotic conjugation reactions and supports the function of glutathione peroxidases in peroxide detoxification.
Glutathione is actively investigated across several research domains, including oxidative stress and redox biology, hepatic detoxification research, immune cell signaling, neurodegeneration research, and age-related cellular decline. Published reviews have positioned GSH as the most abundant low-molecular-weight thiol in mammalian cells and a central player in oxidant defense and electrophile conjugation chemistry (Forman et al., 2009, Molecular Aspects of Medicine). Intracellular GSH depletion has been associated with oxidative-stress-linked cellular dysfunction, making it a key reference compound in redox research.
The peptide is supplied as a lyophilized powder to ensure optimal stability during storage and handling.
See also: NAD⁺, SS-31 10 mg, and FOXO4-DRI.
Specifications
- Purity: 99%
- Quantity: 600 mg
- CAS Number: 70-18-8
- Molecular Formula: C₁₀H₁₇N₃O₆S
- Molecular Weight: ~307.33 g/mol
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