GHK-Cu is a naturally occurring copper-binding tripeptide composed of glycine, histidine, and lysine. It is classified as a bioactive tripeptide-copper complex widely studied for its role in tissue remodeling and cellular signaling research.
In biological systems, GHK binds copper ions to form the bioactive GHK-Cu complex, which functions as a signaling molecule involved in maintaining tissue integrity. The peptide influences extracellular matrix remodeling by stimulating collagen synthesis and modulating matrix metalloproteinase activity. It also engages TGF-beta signaling pathways and supports endothelial-related cellular responses. At the genomic level, GHK-Cu has been shown to influence gene expression patterns associated with aging and cellular renewal.
Research interest in GHK-Cu focuses on its ability to influence extracellular matrix remodeling, stimulate collagen synthesis, modulate inflammatory signaling, and support cellular renewal processes. Investigations have documented its capacity to reset gene expression patterns associated with aging, activating protective and cellular-pathway genes (Pickart & Margolina, 2018, International Journal of Molecular Sciences). Due to its broad biological activity, GHK-Cu is frequently investigated in cellular-pathway biology, skin physiology, and age-related tissue degeneration models. It remains a foundational compound in connective tissue and aging research.
The peptide is supplied as a lyophilized powder to ensure optimal stability during storage and handling.
See also: Epitalon, Snap-8, and MOTS-c 10 mg.
Specifications
- Purity: 99%
- Quantity: 50 mg
- CAS Number: 49557-75-7
- Molecular Formula: C₁₄H₂₄N₆O₄·Cu
- Molecular Weight: ~401.9 g/mol
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