Cortagen is a short peptide bioregulator developed within the Khavinson school of peptide research at the Saint Petersburg Institute of Bioregulation and Gerontology. Classified as a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Pro (AEDP), Cortagen was developed to investigate how minimal peptide sequences interact with cerebral cortex tissue and neuronal-pathway research models. Its compact structure positions Cortagen as a useful research compound for studying tissue-specific peptide signaling in laboratory contexts.
At the cellular and molecular level, Cortagen is studied for its proposed ability to engage with chromatin structure and modulate transcriptional activity within cortical neurons and neural cell models. Research observations within the Khavinson framework suggest that short bioregulator peptides interact with specific DNA regions to influence the expression of genes associated with neuronal signaling balance, neural tissue adaptation, and chromatin-associated epigenetic regulation in nervous-system cell systems. These observations are consistent with the broader proposition that short peptides act as gene-expression regulators within tissues from which their parent peptide complexes were originally extracted.
Research interest in Cortagen centers on nervous-system tissue gene expression studies, neuronal-pathway research models, and chromatin-organization investigations. Comparative work on tissue-specific bioregulators positions Cortagen alongside other neural-targeted oligopeptides used to explore peptidergic regulation of central nervous system biology in cell-culture and animal research models (Khavinson V.K., Anisimov V.N., 2009, Advances in Gerontology). Additional reports within the Khavinson tradition describe how the AEDP sequence influences neuronal gene-expression profiles in cortical research models, supporting continued laboratory investigation of Cortagen in neurobiology and chromatin biology research.
The peptide is supplied as a lyophilized powder to ensure optimal stability during storage and handling.
See also: Pinealon 20 mg, Semax 10 mg, and Cartalax 20 mg.
Specifications
- Purity: 99%
- Quantity: 20 mg
- Molecular Formula: C₁₇H₂₆N₄O₉
- Molecular Weight: ~430.4 g/mol






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